DOTA (1,4,7,10-tetraazacyclododecane-N,N',N″,N‴-tetraacetic acid) is a chelating agent widely employed in diverse scientific fields. Its chemical structure enables the formation of stable complexes with metal ions, making it valuable for various applications. DOTA derivatives have found significant use in chemistry, biology, and medicine. In medical imaging, DOTA is employed to create contrast agents for techniques like magnetic resonance imaging (MRI), positron emission tomography (PET), and single-photon emission computed tomography (SPECT). The stable chelation of DOTA with metal ions facilitates targeted imaging of specific tissues or organs. Additionally, DOTA derivatives are utilized in the development of radiopharmaceuticals for targeted therapy, allowing for precise delivery of therapeutic agents to disease sites. Their ability to selectively bind to cancer cells via conjugation with peptides makes them effective tools for cancer diagnosis and treatment.
CD Bioparticles manufactures and supplies DOTA derivatives for research. Contact us to find out how DOTA derivatives can help your work.