Polyacrylamide, a versatile polymer, has garnered significant attention in the realm of drug delivery due to its unique properties and tunable characteristics. With its high water-absorbing capacity and biocompatibility, polyacrylamide offers a promising platform for the controlled release of pharmaceutical agents. The polymer's ability to form hydrogels, both responsive to environmental stimuli and stimuli-independent, positions it as a valuable candidate for drug delivery applications. Researchers exploit its flexibility to engineer hydrogel formulations that can encapsulate and release therapeutic compounds in a controlled manner, addressing challenges such as sustained drug release and improved bioavailability. Polyacrylamide's biocompatible nature further enhances its appeal for drug delivery, minimizing potential adverse effects on biological systems. This polymer's adaptability allows for the incorporation of various drugs, offering a versatile platform that can be tailored to specific therapeutic requirements.