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Cleavable Peptide Linkers


Peptide linkers are a class of protease cleavable linkers. Peptide linkers are key components of antibody drug conjugates (ADCs) due to their superior plasma stability and controlled load release mechanism. Well-designed linkers help antibodies selectively deliver cytotoxic drugs to tumor cells and deliver drugs accurately at tumor sites. By introducing PEG into the linker, it increases the water solubility of the linker itself and helps fine-tune the drug DMPK.

Cleavable Peptide Linkers

DBCO-C4-Val-Cit-PABC-PNP

Catalog: CDAX095

MW: 859.94

$3290
Cleavable Peptide Linkers

Val-Cit-PAB-OH

Catalog: CDAX007

MW: 379.46

$1320
Cleavable Peptide Linkers

Val-Cit-alcohol

Catalog: CDAX008

MW: 274.32

$720
Cleavable Peptide Linkers

Val-Ala-PAB

Catalog: CDAX009

MW: 293.37

$1900
Cleavable Peptide Linkers

TCO-PEG1-Val-Cit-PABC-PNP

Catalog: CDAX013

MW: 811.89

$2070
Cleavable Peptide Linkers

TCO-PEG1-Val-Cit-PABC-OH

Catalog: CDAX014

MW: 646.79

$1840
Cleavable Peptide Linkers

TCO-PEG1-Val-Cit-OH

Catalog: CDAX015

MW: 541.65

$1120
Cleavable Peptide Linkers

SPDP-Val-Cit-PAB-PNP

Catalog: CDAX018

MW: 741.84

$890
Cleavable Peptide Linkers

SPDP-Val-Cit-PAB-OH

Catalog: CDAX019

MW: 576.73

$800
Cleavable Peptide Linkers

MC-Val-Cit-PAB-PNP

Catalog: CDAX042

MW: 737.8

$1020
Cleavable Peptide Linkers

MC-Val-Cit-PAB-OH

Catalog: CDAX043

MW: 572.7

$2160
Cleavable Peptide Linkers

MC-Val-Cit-OH

Catalog: CDAX044

MW: 467.52

$1480
Cleavable Peptide Linkers

Mc-Val-Ala-PAB-PNP

Catalog: CDAX045

MW: 651.67

$1380
Cleavable Peptide Linkers

Mc-Val-Ala-PAB

Catalog: CDAX046

MW: 486.57

$1630
Cleavable Peptide Linkers

MC-Ala-Ala-Asn(Trt)-OH

Catalog: CDAX047

MW: 709.79

$1180
Cleavable Peptide Linkers

MC(C2)-Val-Cit-PAB-OH

Catalog: CDAX048

MW: 530.58

$1330
Cleavable Peptide Linkers

MC (C5)-Val-Cit

Catalog: CDAX049

MW: 452.51

$960
Cleavable Peptide Linkers

Mal-PEG4-Val-Cit-PAB-PNP

Catalog: CDAX050

MW: 871.9

$1620
Cleavable Peptide Linkers

Mal-PEG4-Val-Cit-PAB-OH

Catalog: CDAX051

MW: 706.8

$1180
Cleavable Peptide Linkers

Mal-PEG2-Val-Cit-PAB-OH

Catalog: CDAX052

MW: 618.7

$1020
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