Compared with visible and near-infrared fluorescence, near-infrared-II (NIR-II, 1000-1700 nm) fluorescence has less scattering and tissue absorption in the organism, and the biological autofluorescence effect is extremely low in this band, which shows the advantages of deeper tissue penetration depth and higher spatial resolution in in-vivo imaging, so NIR-II fluorescence imaging has become the hot direction of the biomedical research. CD Bioparticles can provide some NIR-II dyes with reactive groups,such as NHS esters, azides, and DBCOs, facilitating efficient and specific bioconjugation with biomolecules like antibodies, peptides, and nucleic acids. These dyes are ideal tools for researchers aiming to achieve high-contrast, targeted imaging in deep biological tissues.
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