Poly([alkyl] acrylic acid) and Poly([alkyl] methacrylate) Families

The Poly([alkyl] acrylic acid) and Poly([alkyl] methacrylate) families represent new avenues in the realm of drug delivery, harnessing the versatile properties of acrylic acid and methacrylate monomers. These polymers offer a spectrum of possibilities for designing advanced drug delivery systems with tailored functionalities. Poly([alkyl] acrylic acid) polymers, characterized by the presence of acrylic acid units, provide pH-responsive features, enabling controlled drug release in response to specific physiological conditions. This responsiveness allows for targeted delivery to acidic environments, such as those found in inflamed tissues or within intracellular compartments.

Concurrently, the Poly([alkyl] methacrylate) family, distinguished by methacrylate monomers, affords a platform for developing drug carriers with tunable hydrophobicity and biocompatibility. These polymers can encapsulate hydrophobic drugs efficiently, addressing challenges related to drug solubility and bioavailability. Additionally, the synthesis versatility of methacrylate derivatives allows for the creation of stimuli-responsive drug carriers, responding to external triggers like light or temperature for controlled release.