Clipos™ Nirmatrelvir (PF-07321332) Encapsulated Liposomes
Specifications
Description
|
PEGylated liposomes containing SARS-CoV-2 Mpro inhibitor Nirmatrelvir (PF-07321332). Nirmatrelvir (PF-07321332) is a reversible covalent inhibitor of the SARS-CoV-2 main protease (Mpro, also referred to as 3CL protease or 3CLpro) that binds to the catalytic cysteine (Cys145) and has a reported ki of 3.11 nM. The liposomes are PEGylated for optimal in vivo performance. For preclinical research use only. |
Lipid composition
|
PEGylated Liposomes |
Liposome Size
|
70-120 nm |
Lipid Molar Concentration
|
60 mM |
Encapsulated Drug
|
Nirmatrelvir |
Drug concentration
|
10.0 mg/mL (± ~5%) |
Inside Buffer
|
292 mM sucrose, 0.5% DPBS (1X) |
Outside Buffer
|
292 mM sucrose, 0.5% DPBS (1X) |
Storage
|
2 °C to 8 °C (do not freeze) |
Shelf-life
|
At least 1 month |
CAS No.
|
2628280-40-8 |
Related Products